Voltage-gated calcium (Cav) channels are a prerequisite for signal transmission at the first olfactory sensory neuron (OSN) synapse within the glomeruli of the main olfactory bulb (MOB).We showed previously that the N-type Cav channel subunit Cav2.2 is present in the vast majority of glomeruli and plays a central role in presynaptic transmitter rel

Abstract Objectives Considering the therapeutic potential of honey and Nigella sativa (HNS) in coronavirus disease 2019 (COVID-19) patients, the objective of the study is defined to evaluate the prophylactic role of HNS.Trial design The study is a randomized, placebo-controlled, adaptive clinical trial with parallel group design, superiority framew

In the present article the basic aspects of activity of Romanian Orthodox Mission in Transnistria during the Second World War (1941-1944) are analyzed.The author concludes that the main objective of Romanian politics was the Charging Stand re-Christianization of the occupied territory of the USSR.The situation of the Orthodox Church in Transnistria

Despite treatment with agents that enhance beta-cell function and insulin action, reduction in beta-cell mass is relentless in patients with insulin resistance and type 2 diabetes mellitus.Insulin resistance is characterized by impaired signaling through the insulin/insulin receptor/insulin receptor substrate/PI-3K/Akt pathway, leading to elevation

Abstract Background As a recently discovered member of the DPANN superphylum, Woesearchaeota account for a wide diversity of 16S rRNA gene sequences, but their ecology, evolution, and metabolism remain largely unknown.Results Here, we assembled 133 global clone libraries/studies and 19 publicly available genomes to profile these patterns for Woesea